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The selective butyrylcholinesterase inhibitor UW-MD-95 shows symptomatic and neuroprotective effects in a pharmacological mouse model of Alzheimer's disease.

Allison CarlesMatthias HoffmannMatthias ScheinerLucie CrouzierChristelle Bertrand-GadayArnaud ChatonnetMichael DeckerTangui Maurice
Published in: CNS neuroscience & therapeutics (2024)
accumulation that could suggest a novel mechanism of neuroprotection.
Keyphrases
  • mouse model
  • cognitive decline
  • brain injury
  • molecular dynamics
  • cerebral ischemia
  • subarachnoid hemorrhage
  • blood brain barrier