Laser technology in proctological diseases: is it really the wave of the future?
Stefano SolariJacopo MartellucciAlfredo AnnicchiaricoMaximilian ScheiterleCarlo BergaminiPaolo ProsperiPublished in: Updates in surgery (2023)
Different types of lasers have been applied for various proctological conditions. We discuss about published articles regarding the application of lasers, with concern about evidence-based use of these techniques and technologies. We performed a literature search about laser treatments for proctological conditions. 55 studies were included for the final revision. Meta-analysis of data was not performed because of heterogeneity of study designs and outcome measures. A scoping review was performed. Laser treatments for hemorrhoids require a shorter operative time and show less postoperative pain and bleeding compared to conventional hemorrhoidectomy, but are more expensive. Studies are heterogeneous in design, endpoints, postoperative assessment, length of follow-up and outcome measures. Only 3 RCTs are available and only three studies evaluate long-term outcomes. FiLaC (fistula laser closure) was initially described in 2011 for the treatment of anal fistula. In the published studies the reported healing rates vary between 20 and 82%, and the ideal indication is yet to be defined. Studies with long-term follow-up are lacking. SiLaT (sinus laser treatment) applied the technology used for FiLaC to the treatment of pilonidal sinus disease. This technique had less perioperative pain and shorter hospital stay, but a lower primary healing rate when compared to traditional techniques. Available data is very limited, and no randomized trials are published to date. Laser assisted techniques are a viable, minimally invasive, but expensive option for the treatment of several proctological conditions. Further researches are needed to assess if patients could benefit of their use, and for what indication.
Keyphrases
- minimally invasive
- systematic review
- patients undergoing
- high speed
- case control
- postoperative pain
- emergency department
- chronic kidney disease
- chronic pain
- randomized controlled trial
- newly diagnosed
- machine learning
- ejection fraction
- big data
- combination therapy
- pain management
- prognostic factors
- spinal cord injury
- mass spectrometry
- patient reported outcomes
- spinal cord
- replacement therapy
- smoking cessation
- deep learning
- adverse drug