Mechanosensitive Stem-Cell Genes and Klotho in Atherosclerotic Aortas: Regulating Spatially Deranged Expression Patterns Using Colchicine Regimens.
Konstantinos S MylonasPanagiotis SarantisAlkistis KapelouzouMichalis V KaramouzisEmmanouil Ioannis KapetanakisKonstantinos KontzoglouDimitrios C IliopoulosNikolaos NikiteasDimitrios SchizasPublished in: Journal of clinical medicine (2022)
Overall, the aortic expression pattern of mechanosensitive genes seems to be spatially influenced by a hyperlipidemic diet and can be modified using colchicine-based therapy.