Tumour-stroma ratio has poor prognostic value in nonpedunculated T1 colorectal cancer: A multicentre case-cohort study.
Hao DangGabi W van PeltKrijn J C HaasnootYara BackesSjoerd G EliasTom C J SeerdenMatthijs P SchwartzBernhard W M SpanierWouter H de Vos Tot Nederveen CappelJeroen D van BergeijkKoen KesselsJoost M J GeesingJohn N GroenFrank Ter BorgFrank H J WolfhagenCornelis A SeldenrijkMihaela G RaicuAnya N MilneAnja U G van LentLodewijk A A BrosensG Johan A OfferhausPeter D SiersemaRob A E M TollenaarJames C H HardwickLukas J A C HawinkelsLeon M G MoonsMiangela M LacleWilma E MeskerJurjen J Boonstranull nullPublished in: United European gastroenterology journal (2021)
Our study emphasises that existing prognosticators may not be simply extrapolated to T1 colorectal cancers, even though their prognostic value has been widely validated in more advanced-stage tumours.