Human levator veli palatini muscle: a novel source of mesenchymal stromal cells for use in the rehabilitation of patients with congenital craniofacial malformations.
Daniela Franco BuenoGerson Shigueru KabayashiCarla Cristina Gomes PinheiroDaniela Y S TanikawaCassio Eduardo Raposo-AmaralDiogenes Laercio RochaJosé Ricardo Muniz FerreiraYoichiro ShibuyaAkishige HokugoReza JarrahyPatricia A ZuKMaria Rita Passos-BuenoPublished in: Stem cell research & therapy (2020)
Cells derived from levator veli palatini muscle have phenotypic characteristics similar to other mesenchymal stromal cells, both in vitro and in vivo. Our findings suggest that these cells may have clinical relevance in the surgical rehabilitation of patients with cleft palate and other craniofacial anomalies characterized by significant bone deficit.