Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017.

Helen J CurtisJohn M DennisBeverley M ShieldsAlex J WalkerSeb BaconAndrew T HattersleyAngus G Jones Alex J Walker

Published in: Diabetes, obesity & metabolism (2018)

In England there is extensive geographical variation in the prescribing of diabetes drugs after metformin, and increasing use of higher-cost DPP-4 inhibitors and SGLT-2 inhibitors compared with low-cost sulphonylureas. Our findings strongly support the case for comparative effectiveness trials of current diabetes drugs.

Keyphrases

type diabetes
low cost
cardiovascular disease
glycemic control
primary care
drug induced
skeletal muscle
insulin resistance
metabolic syndrome
weight loss