Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017.
Helen J CurtisJohn M DennisBeverley M ShieldsAlex J WalkerSeb BaconAndrew T HattersleyAngus G JonesAlex J WalkerPublished in: Diabetes, obesity & metabolism (2018)
In England there is extensive geographical variation in the prescribing of diabetes drugs after metformin, and increasing use of higher-cost DPP-4 inhibitors and SGLT-2 inhibitors compared with low-cost sulphonylureas. Our findings strongly support the case for comparative effectiveness trials of current diabetes drugs.