Alex J Walker (B Goldacre, Ben Goldacre)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 78

Top Topics

Coronavirus Disease

Electronic Health Record

Top Venues

BMJ (Clinical research ed.)

Annals of internal medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Lisa E M Hopcroft, Helen J Curtis, Richard Croker, Felix Pretis, Peter Inglesby, David Evans, Sebastian C J Bacon, Alex J Walker, Alex J Walker, Brian Mackenna
Data-Driven Identification of Potentially Successful Intervention Implementations Using 5 Years of Opioid Prescribing Data: Retrospective Database Study. JMIR public health and surveillance 10 (2024)
Elsie M F Horne, William J Hulme, Edward P K Parker, Ruth H Keogh, Elizabeth J Williamson, Venexia M Walker, Tom M Palmer, Rachel Denholm, Rochelle Knight, Helen J Curtis, Alex J Walker, Colm D Andrews, Amir Mehrkar, Jessica Morley, Brian Mackenna, Sebastian C J Bacon, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne, null null
Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP. Epidemiology (Cambridge, Mass.) 35 (4) (2024)
Shalini Santhakumaran, Louis Fisher, Viyaasan Mahalingasivam, Lucy Plumb, Edward P K Parker, Retha Steenkamp, Caroline Morton, Amir Mehrkar, Sebastian Bacon, Sue Lyon, Rob Konstant-Hambling, Alex J Walker, Brian MacKenna, Laurie A Tomlinson, Dorothea Nitsch
Identification of patients undergoing chronic kidney replacement therapy in primary and secondary care data: validation study based on OpenSAFELY and UK Renal Registry. BMJ medicine 3 (1) (2024)
Elsie M F Horne, William J Hulme, Edward P K Parker, Ruth H Keogh, Elizabeth J Williamson, Venexia M Walker, Tom M Palmer, Rachel Denholm, Rochelle Knight, Helen J Curtis, Alex J Walker, Colm D Andrews, Amir Mehrkar, Jessica Morley, Brian Mackenna, Sebastian C J Bacon, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne, null null
Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP. Epidemiology (Cambridge, Mass.) 35 (4) (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology (2024)
Christine Cunningham, Louis Fisher, Christopher Wood, Victoria Speed, Andrew D Brown, Helen Curtis, Rose Higgins, Richard Croker, Ben Fc Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian Cj Bacon, Elizabeth Beech, Kieran S Hand, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Liam C Hart, Chris Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP. BMJ medicine 3 (1) (2024)
Lisa E M Hopcroft, Helen J Curtis, Richard Croker, Felix Pretis, Peter Inglesby, David Evans, Sebastian C J Bacon, Alex J Walker, Alex J Walker, Brian Mackenna
Data-Driven Identification of Potentially Successful Intervention Implementations Using 5 Years of Opioid Prescribing Data: Retrospective Database Study. JMIR public health and surveillance 10 (2024)
Nicholas J DeVito, Jessica Morley, James Andrew Smith, Henry Drysdale, Alex J Walker, Carl J Heneghan
Availability of results of clinical trials registered on EU Clinical Trials Register: cross sectional audit study. BMJ medicine 3 (1) (2024)
Andrea L Schaffer, Robin Y Park, John Tazare, Krishnan Bhaskaran, Brian MacKenna, Spiros Denaxas, Iain Dillingham, Sebastian C J Bacon, Amir Mehrkar, Christopher Bates, Alex J Walker, Felix Greaves, John Macleod, null null, null null, Laurie A Tomlinson, Alex J Walker
Changes in sick notes associated with COVID-19 from 2020 to 2022: a cohort study in 24 million primary care patients in OpenSAFELY-TPP. BMJ open 14 (7) (2024)
Andrea L Schaffer, Robin Y Park, John Tazare, Krishnan Bhaskaran, Brian MacKenna, Spiros Denaxas, Iain Dillingham, Sebastian C J Bacon, Amir Mehrkar, Christopher Bates, Alex J Walker, Felix Greaves, John Macleod, null null, null null, Laurie A Tomlinson, Alex J Walker
Changes in sick notes associated with COVID-19 from 2020 to 2022: a cohort study in 24 million primary care patients in OpenSAFELY-TPP. BMJ open 14 (7) (2024)
Shalini Santhakumaran, Louis Fisher, Viyaasan Mahalingasivam, Lucy Plumb, Edward P K Parker, Retha Steenkamp, Caroline Morton, Amir Mehrkar, Sebastian Bacon, Sue Lyon, Rob Konstant-Hambling, Alex J Walker, Brian MacKenna, Laurie A Tomlinson, Dorothea Nitsch
Identification of patients undergoing chronic kidney replacement therapy in primary and secondary care data: validation study based on OpenSAFELY and UK Renal Registry. BMJ medicine 3 (1) (2024)
Odette Wegwarth, Tammy C Hoffmann, Alex J Walker, Claudia D Spies, Helge A Giese
General practitioners' risk literacy and real-world prescribing of potentially hazardous drugs: a cross-sectional study. BMJ quality & safety (2024)
Martina Fonseca, Brian Mackenna, Amir Mehrkar, null null, Caroline E Walters, George Hickman, Jonathan Pearson, Louis Fisher, Peter Inglesby, Sebastian C J Bacon, Simon Davy, William J Hulme, Alex J Walker, Ofra Koffman, Minal Bakhai
The Use of Online Consultation Systems or Remote Consulting in England Characterized Through the Primary Care Health Records of 53 Million People in the OpenSAFELY Platform: Retrospective Cohort Study. JMIR public health and surveillance 10 (2024)
Milan Wiedemann, Victoria Speed, Christine Cunningham, Rose Higgins, Helen J Curtis, Colm D Andrews, Louis Fisher, Lisa Hopcroft, Christopher T Rentsch, Viyaasan Mahalingasivam, Laurie A Tomlinson, Caroline E Morton, Miriam Samuel, Amelia Green, Christopher Wood, Andrew D Brown, Jon Massey, Caroline Walters, Rebecca M Smith, Peter Inglesby, David Evans, Steven Maude, Iain Dillingham, Alex J Walker, Jessica Morley, Amir Mehrkar, Sebastian C J Bacon, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Richard J McManus, Alex J Walker, Brian Mackenna
Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in OpenSAFELY. Open heart 11 (2) (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology 90 (7) (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology 90 (7) (2024)
Lisa E M Hopcroft, Helen J Curtis, Richard Croker, Felix Pretis, Peter Inglesby, David Evans, Sebastian C J Bacon, Alex J Walker, Alex J Walker, Brian Mackenna
Data-Driven Identification of Potentially Successful Intervention Implementations Using 5 Years of Opioid Prescribing Data: Retrospective Database Study. JMIR public health and surveillance 10 (2024)
Elsie M F Horne, William J Hulme, Edward P K Parker, Ruth H Keogh, Elizabeth J Williamson, Venexia M Walker, Tom M Palmer, Rachel Denholm, Rochelle Knight, Helen J Curtis, Alex J Walker, Colm D Andrews, Amir Mehrkar, Jessica Morley, Brian Mackenna, Sebastian C J Bacon, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne, null null
Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP. Epidemiology (Cambridge, Mass.) 35 (4) (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology 90 (7) (2024)
Nicholas J DeVito, Jessica Morley, James Andrew Smith, Henry Drysdale, Alex J Walker, Carl J Heneghan
Availability of results of clinical trials registered on EU Clinical Trials Register: cross sectional audit study. BMJ medicine 3 (1) (2024)
Nicholas J DeVito, Jessica Morley, James Andrew Smith, Henry Drysdale, Alex J Walker, Carl J Heneghan
Availability of results of clinical trials registered on EU Clinical Trials Register: cross sectional audit study. BMJ medicine 3 (1) (2024)
Christine Cunningham, Louis Fisher, Christopher Wood, Victoria Speed, Andrew D Brown, Helen Curtis, Rose Higgins, Richard Croker, Ben Fc Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian Cj Bacon, Elizabeth Beech, Kieran S Hand, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Liam C Hart, Chris Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP. BMJ medicine 3 (1) (2024)
Odette Wegwarth, Tammy C Hoffmann, Alex J Walker, Claudia D Spies, Helge A Giese
General practitioners' risk literacy and real-world prescribing of potentially hazardous drugs: a cross-sectional study. BMJ quality & safety (2024)
null null, Christopher Wood, Victoria Speed, Louis Fisher, Helen J Curtis, Andrea L Schaffer, Alex J Walker, Richard Croker, Andrew D Brown, Christine Cunningham, William J Hulme, Colm D Andrews, Ben F C Butler-Cole, David Evans, Peter Inglesby, Iain Dillingham, Sebastian C J Bacon, Simon Davy, Tom Ward, George Hickman, Lucy Bridges, Thomas O'Dwyer, Steven Maude, Rebecca M Smith, Amir Mehrkar, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Alex J Walker, Brian Mackenna
The impact of COVID-19 on medication reviews in English primary care. An OpenSAFELY-TPP analysis of 20 million adult electronic health records. British journal of clinical pharmacology 90 (7) (2024)
Andrea L Schaffer, Robin Y Park, John Tazare, Krishnan Bhaskaran, Brian MacKenna, Spiros Denaxas, Iain Dillingham, Sebastian C J Bacon, Amir Mehrkar, Christopher Bates, Alex J Walker, Felix Greaves, John Macleod, null null, null null, Laurie A Tomlinson, Alex J Walker
Changes in sick notes associated with COVID-19 from 2020 to 2022: a cohort study in 24 million primary care patients in OpenSAFELY-TPP. BMJ open 14 (7) (2024)
Shalini Santhakumaran, Louis Fisher, Viyaasan Mahalingasivam, Lucy Plumb, Edward P K Parker, Retha Steenkamp, Caroline Morton, Amir Mehrkar, Sebastian Bacon, Sue Lyon, Rob Konstant-Hambling, Alex J Walker, Brian MacKenna, Laurie A Tomlinson, Dorothea Nitsch
Identification of patients undergoing chronic kidney replacement therapy in primary and secondary care data: validation study based on OpenSAFELY and UK Renal Registry. BMJ medicine 3 (1) (2024)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine (2023)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine 176 (5) (2023)
null null, Edward Pk Parker, John Tazare, William J Hulme, Christopher Bates, Edward J Carr, Jonathan Cockburn, Helen J Curtis, Louis Fisher, Amelia Ca Green, Sam Harper, Frank Hester, Elsie Mf Horne, Fiona Loud, Susan Lyon, Viyaasan Mahalingasivam, Amir Mehrkar, Linda Nab, John Parry, Shalini Santhakumaran, Retha Steenkamp, Jonathan A C Sterne, Alex J Walker, Elizabeth J Williamson, Michelle Willicombe, Bang Zheng, Alex J Walker, Dorothea Nitsch, Laurie A Tomlinson
Factors associated with COVID-19 vaccine uptake in people with kidney disease: an OpenSAFELY cohort study. BMJ open 13 (1) (2023)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine 176 (5) (2023)
Amelia C A Green, Helen J Curtis, Rose Higgins, Linda Nab, Viyaasan Mahalingasivam, Rebecca M Smith, Amir Mehrkar, Peter Inglesby, Henry Drysdale, Nicholas J DeVito, Richard Croker, Christopher T Rentsch, Krishnan Bhaskaran, John Tazare, Bang Zheng, Colm D Andrews, Sebastian C J Bacon, Simon Davy, Iain Dillingham, David Evans, Louis Fisher, George Hickman, Lisa E M Hopcroft, William J Hulme, Jon Massey, Orla MacDonald, Jessica Morley, Caroline E Morton, Robin Y Park, Alex J Walker, Tom Ward, Milan Wiedemann, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Stephen J W Evans, Alex J Walker, Laurie A Tomlinson, Brian Mackenna
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY. BMJ medicine 2 (1) (2023)
null null, Edward Pk Parker, John Tazare, William J Hulme, Christopher Bates, Edward J Carr, Jonathan Cockburn, Helen J Curtis, Louis Fisher, Amelia Ca Green, Sam Harper, Frank Hester, Elsie Mf Horne, Fiona Loud, Susan Lyon, Viyaasan Mahalingasivam, Amir Mehrkar, Linda Nab, John Parry, Shalini Santhakumaran, Retha Steenkamp, Jonathan A C Sterne, Alex J Walker, Elizabeth J Williamson, Michelle Willicombe, Bang Zheng, Alex J Walker, Dorothea Nitsch, Laurie A Tomlinson
Factors associated with COVID-19 vaccine uptake in people with kidney disease: an OpenSAFELY cohort study. BMJ open 13 (1) (2023)
null null, Edward Pk Parker, John Tazare, William J Hulme, Christopher Bates, Edward J Carr, Jonathan Cockburn, Helen J Curtis, Louis Fisher, Amelia Ca Green, Sam Harper, Frank Hester, Elsie Mf Horne, Fiona Loud, Susan Lyon, Viyaasan Mahalingasivam, Amir Mehrkar, Linda Nab, John Parry, Shalini Santhakumaran, Retha Steenkamp, Jonathan A C Sterne, Alex J Walker, Elizabeth J Williamson, Michelle Willicombe, Bang Zheng, Alex J Walker, Dorothea Nitsch, Laurie A Tomlinson
Factors associated with COVID-19 vaccine uptake in people with kidney disease: an OpenSAFELY cohort study. BMJ open 13 (1) (2023)
Bang Zheng, Jacqueline Campbell, Edward J Carr, John Tazare, Linda Nab, Viyaasan Mahalingasivam, Amir Mehrkar, Shalini Santhakumaran, Retha Steenkamp, Fiona Loud, Susan Lyon, Miranda Scanlon, William J Hulme, Amelia C A Green, Helen J Curtis, Louis Fisher, Edward Parker, Alex J Walker, Ian Douglas, Stephen Evans, Brian MacKenna, Samira Bell, Laurie A Tomlinson, Dorothea Nitsch, null null
Comparative effectiveness of sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in patients on kidney replacement therapy: observational study using the OpenSAFELY-UKRR and SRR databases. Clinical kidney journal 16 (11) (2023)
Emily Herrett, Keith Tomlin, Liang-Yu Lin, Laurie A Tomlinson, Mark Jit, Andrew Briggs, Michael Marks, Frank Sandmann, John Parry, Christopher Bates, Jessica Morley, Seb Bacon, Benjamin Butler-Cole, Viyaasan Mahalingasivam, Alan Dennison, Deb Smith, Ethan Gabriel, Amir Mehrkar, Alex J Walker, Liam Smeeth, Rosalind M M Eggo
Protocol for an OpenSAFELY cohort study collecting patient-reported outcome measures using the TPP Airmid smartphone application and linked big data to quantify the health and economic costs of long COVID (OpenPROMPT). BMJ open 13 (2) (2023)
Amelia C A Green, Helen J Curtis, Rose Higgins, Linda Nab, Viyaasan Mahalingasivam, Rebecca M Smith, Amir Mehrkar, Peter Inglesby, Henry Drysdale, Nicholas J DeVito, Richard Croker, Christopher T Rentsch, Krishnan Bhaskaran, John Tazare, Bang Zheng, Colm D Andrews, Sebastian C J Bacon, Simon Davy, Iain Dillingham, David Evans, Louis Fisher, George Hickman, Lisa E M Hopcroft, William J Hulme, Jon Massey, Orla MacDonald, Jessica Morley, Caroline E Morton, Robin Y Park, Alex J Walker, Tom Ward, Milan Wiedemann, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Stephen J W Evans, Alex J Walker, Laurie A Tomlinson, Brian Mackenna
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY. BMJ medicine 2 (1) (2023)
Emily Herrett, Keith Tomlin, Liang-Yu Lin, Laurie A Tomlinson, Mark Jit, Andrew Briggs, Michael Marks, Frank Sandmann, John Parry, Christopher Bates, Jessica Morley, Seb Bacon, Benjamin Butler-Cole, Viyaasan Mahalingasivam, Alan Dennison, Deb Smith, Ethan Gabriel, Amir Mehrkar, Alex J Walker, Liam Smeeth, Rosalind M M Eggo
Protocol for an OpenSAFELY cohort study collecting patient-reported outcome measures using the TPP Airmid smartphone application and linked big data to quantify the health and economic costs of long COVID (OpenPROMPT). BMJ open 13 (2) (2023)
Helen J Curtis, Brian Mackenna, Milan Wiedemann, Louis Fisher, Richard Croker, Caroline E Morton, Peter Inglesby, Alex J Walker, Jessica Morley, Amir Mehrkar, Sebastian C J Bacon, George Hickman, David Evans, Tom Ward, Simon Davy, William J Hulme, Orla Macdonald, Robin Conibere, Tom Lewis, Martin Myers, Shamila Wanninayake, Kiren Collison, Charles Drury, Miriam Samuel, Harpreet Sood, Andrea Cipriani, Seena Fazel, Manuj Sharma, Wasim Baqir, Christopher Bates, John Parry, Alex J Walker, null null
OpenSAFELY NHS Service Restoration Observatory 2: changes in primary care clinical activity in England during the COVID-19 pandemic. The British journal of general practice : the journal of the Royal College of General Practitioners (2023)
Emily Herrett, Keith Tomlin, Liang-Yu Lin, Laurie A Tomlinson, Mark Jit, Andrew Briggs, Michael Marks, Frank Sandmann, John Parry, Christopher Bates, Jessica Morley, Seb Bacon, Benjamin Butler-Cole, Viyaasan Mahalingasivam, Alan Dennison, Deb Smith, Ethan Gabriel, Amir Mehrkar, Alex J Walker, Liam Smeeth, Rosalind M M Eggo
Protocol for an OpenSAFELY cohort study collecting patient-reported outcome measures using the TPP Airmid smartphone application and linked big data to quantify the health and economic costs of long COVID (OpenPROMPT). BMJ open 13 (2) (2023)
Louis Fisher, Lisa E M Hopcroft, Sarah Rodgers, James Barrett, Kerry Oliver, Anthony J Avery, Dai Evans, Helen J Curtis, Richard Croker, Orla Macdonald, Jessica Morley, Amir Mehrkar, Sebastian C J Bacon, Simon Davy, Iain Dillingham, David Evans, George Hickman, Peter Inglesby, Caroline E Morton, Becky Smith, Tom Ward, William J Hulme, Amelia C A Green, Jon Massey, Alex J Walker, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Shaun O'Hanlon, Alex Eavis, Richard Jarvis, Dima Avramov, Paul Griffiths, Aaron Fowles, Nasreen Parkes, Alex J Walker, Brian Mackenna
Changes in medication safety indicators in England throughout the covid-19 pandemic using OpenSAFELY: population based, retrospective cohort study of 57 million patients using federated analytics. BMJ medicine 2 (1) (2023)
Lisa E M Hopcroft, Jon Massey, Helen J Curtis, Brian Mackenna, Richard Croker, Andrew D Brown, Thomas O'Dwyer, Orla Macdonald, David Evans, Peter Inglesby, Sebastian C J Bacon, Alex J Walker, Alex J Walker
Data-Driven Identification of Unusual Prescribing Behavior: Analysis and Use of an Interactive Data Tool Using 6 Months of Primary Care Data From 6500 Practices in England. JMIR medical informatics 11 (2023)
Ciarán D McInerney, Alwyn Kotze, Sebastian C J Bacon, J E Cutting, Louis Fisher, Alex J Walker, Owen A Johnson, Justin Kua, D McGuckin, Amir Mehrkar, null null, S Ramani Moonesinghe
Postoperative mortality and complications in patients with and without pre-operative SARS-CoV-2 infection: a service evaluation of 24 million linked records using OpenSAFELY. Anaesthesia (2023)
null null, Edward Pk Parker, John Tazare, William J Hulme, Christopher Bates, Edward J Carr, Jonathan Cockburn, Helen J Curtis, Louis Fisher, Amelia Ca Green, Sam Harper, Frank Hester, Elsie Mf Horne, Fiona Loud, Susan Lyon, Viyaasan Mahalingasivam, Amir Mehrkar, Linda Nab, John Parry, Shalini Santhakumaran, Retha Steenkamp, Jonathan A C Sterne, Alex J Walker, Elizabeth J Williamson, Michelle Willicombe, Bang Zheng, Alex J Walker, Dorothea Nitsch, Laurie A Tomlinson
Factors associated with COVID-19 vaccine uptake in people with kidney disease: an OpenSAFELY cohort study. BMJ open 13 (1) (2023)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine 176 (5) (2023)
William J Hulme, Elizabeth J Williamson, Elsie M F Horne, Amelia C A Green, Helen I McDonald, Alex J Walker, Helen J Curtis, Caroline E Morton, Brian Mackenna, Richard Croker, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Laurie A Tomlinson, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Tom M Palmer, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data. Annals of internal medicine (2023)
Emily Herrett, Keith Tomlin, Liang-Yu Lin, Laurie A Tomlinson, Mark Jit, Andrew Briggs, Michael Marks, Frank Sandmann, John Parry, Christopher Bates, Jessica Morley, Seb Bacon, Benjamin Butler-Cole, Viyaasan Mahalingasivam, Alan Dennison, Deb Smith, Ethan Gabriel, Amir Mehrkar, Alex J Walker, Liam Smeeth, Rosalind M M Eggo
Protocol for an OpenSAFELY cohort study collecting patient-reported outcome measures using the TPP Airmid smartphone application and linked big data to quantify the health and economic costs of long COVID (OpenPROMPT). BMJ open 13 (2) (2023)
null null, Edward Pk Parker, John Tazare, William J Hulme, Christopher Bates, Edward J Carr, Jonathan Cockburn, Helen J Curtis, Louis Fisher, Amelia Ca Green, Sam Harper, Frank Hester, Elsie Mf Horne, Fiona Loud, Susan Lyon, Viyaasan Mahalingasivam, Amir Mehrkar, Linda Nab, John Parry, Shalini Santhakumaran, Retha Steenkamp, Jonathan A C Sterne, Alex J Walker, Elizabeth J Williamson, Michelle Willicombe, Bang Zheng, Alex J Walker, Dorothea Nitsch, Laurie A Tomlinson
Factors associated with COVID-19 vaccine uptake in people with kidney disease: an OpenSAFELY cohort study. BMJ open 13 (1) (2023)
Georgia C Richards, Jeffrey K Aronson, Brian Mackenna, Alex J Walker, Frederick David Richard Hobbs, Carl J Heneghan
Sales of Over-the-Counter Products Containing Codeine in 31 Countries, 2013-2019: A Retrospective Observational Study. Drug safety 45 (3) (2022)
Brian Mackenna, Helen J Curtis, Lisa E M Hopcroft, Alex J Walker, Richard Croker, Orla Macdonald, Stephen J W Evans, Peter Inglesby, David Evans, Jessica Morley, Sebastian C J Bacon, Alex J Walker
Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review. JMIR medical informatics 10 (12) (2022)
Agnieszka Lemanska, Colm D Andrews, Louis Fisher, Ben Butler-Cole, Amir Mehrkar, Keith J Roberts, Alex J Walker, Alex J Walker, null null, Brian MacKenna
The impact of COVID-19 on prescribing of pancreatic enzyme replacement therapy for people with unresectable pancreatic cancer in England. A cohort study using OpenSafely-TPP. medRxiv : the preprint server for health sciences (2022)
Kevin Wing, Daniel J Grint, Rohini Mathur, Hamish P Gibbs, George Hickman, Emily Nightingale, Anna Schultze, Harriet Forbes, Vahe Nafilyan, Krishnan Bhaskaran, Elizabeth J Williamson, Thomas House, Lorenzo Pellis, Emily Herrett, Nileesa Gautam, Helen J Curtis, Christopher T Rentsch, Angel Y S Wong, Brian MacKenna, Amir Mehrkar, Seb Bacon, Ian J Douglas, Stephen J W Evans, Laurie Tomlinson, Alex J Walker, Rosalind M Eggo
Association between household composition and severe COVID-19 outcomes in older people by ethnicity: an observational cohort study using the OpenSAFELY platform. International journal of epidemiology (2022)
Elsie M F Horne, William J Hulme, Ruth H Keogh, Tom M Palmer, Elizabeth J Williamson, Edward P K Parker, Amelia C A Green, Venexia M Walker, Alex J Walker, Helen J Curtis, Louis Fisher, Brian Mackenna, Richard Croker, Lisa E M Hopcroft, Robin Y Park, Jon Massey, Jessica Morley, Amir Mehrkar, Sebastian C J Bacon, David Evans, Peter Inglesby, Caroline E Morton, George Hickman, Simon Davy, Tom Ward, Iain Dillingham, Alex J Walker, Miguel A Hernán, Jonathan A C Sterne
Waning effectiveness of BNT162b2 and ChAdOx1 covid-19 vaccines over six months since second dose: OpenSAFELY cohort study using linked electronic health records. BMJ (Clinical research ed.) 378 (2022)
Brian Mackenna, Helen J Curtis, Lisa E M Hopcroft, Alex J Walker, Richard Croker, Orla Macdonald, Stephen J W Evans, Peter Inglesby, David Evans, Jessica Morley, Sebastian C J Bacon, Alex J Walker
Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review. JMIR medical informatics 10 (12) (2022)
Olivia V Swann, Nazir I Lone, Ewen M Harrison, Laurie A Tomlinson, Alex J Walker, Michael J Seaborne, Louisa Pollock, James Farrell, Peter S Hall, Sohan Seth, Thomas C Williams, Jennifer Preston, J Samantha Ainsworth, Freya F Semple, J Kenneth Baillie, Vittal Srinivasa Katikireddi, Ashley Akbari, Ronan A Lyons, Colin R Simpson, Malcolm G Semple, Alex J Walker, Sinead Brophy, Aziz Sheikh, Annemarie B Docherty
Studying the Long-term Impact of COVID-19 in Kids (SLICK). Healthcare use and costs in children and young people following community-acquired SARS-CoV-2 infection: protocol for an observational study using linked primary and secondary routinely collected healthcare data from England, Scotland and Wales. BMJ open 12 (11) (2022)
William J Hulme, Elizabeth J Williamson, Amelia C A Green, Krishnan Bhaskaran, Helen I McDonald, Christopher T Rentsch, Anna Schultze, John Tazare, Helen J Curtis, Alex J Walker, Laurie A Tomlinson, Tom M Palmer, Elsie M F Horne, Brian Mackenna, Caroline E Morton, Amir Mehrkar, Jessica Morley, Louis Fisher, Sebastian C J Bacon, David Evans, Peter Inglesby, George Hickman, Simon Davy, Tom Ward, Richard Croker, Rosalind M M Eggo, Angel Yun Wong, Rohini Mathur, Kevin Wing, Harriet J Forbes, Daniel J Grint, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Jonathan A C Sterne, Miguel A Hernán, Alex J Walker
Comparative effectiveness of ChAdOx1 versus BNT162b2 covid-19 vaccines in health and social care workers in England: cohort study using OpenSAFELY. BMJ (Clinical research ed.) 378 (2022)
null null, Amelia Green, Helen Curtis, William Hulme, Elizabeth Williamson, Helen McDonald, Krishnan Bhaskaran, Christopher Rentsch, Anna Schultze, Brian MacKenna, Viyaasan Mahalingasivam, Laurie Tomlinson, Alex Walker, Louis Fisher, Jon Massey, Colm Andrews, Lisa Hopcroft, Caroline Morton, Richard Croker, Jessica Morley, Amir Mehrkar, Seb Bacon, David Evans, Peter Inglesby, George Hickman, Tom Ward, Simon Davy, Rohini Mathur, John Tazare, Rosalind Eggo, Kevin Wing, Angel Wong, Harriet Forbes, Chris Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Ian Douglas, Stephen Evans, Liam Smeeth, Alex J Walker
Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: a cohort study from OpenSAFELY. BMC medicine 20 (1) (2022)
Brian Mackenna, Helen J Curtis, Lisa E M Hopcroft, Alex J Walker, Richard Croker, Orla Macdonald, Stephen J W Evans, Peter Inglesby, David Evans, Jessica Morley, Sebastian C J Bacon, Alex J Walker
Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review. JMIR medical informatics 10 (12) (2022)
null null, Elizabeth J Williamson, John Tazare, Krishnan Bhaskaran, Helen I McDonald, Alex J Walker, Laurie Tomlinson, Kevin Wing, Sebastian Bacon, Chris Bates, Helen J Curtis, Harriet J Forbes, Caroline Minassian, Caroline E Morton, Emily Nightingale, Amir Mehrkar, David Evans, Brian D Nicholson, David A Leon, Peter Inglesby, Brian MacKenna, Nicholas G Davies, Nicholas J DeVito, Henry Drysdale, Jonathan Cockburn, William J Hulme, Jessica Morley, Ian Douglas, Christopher T Rentsch, Rohini Mathur, Angel Wong, Anna Schultze, Richard Croker, John Parry, Frank Hester, Sam Harper, Richard Grieve, David A Harrison, Ewout W Steyerberg, Rosalind M Eggo, Karla Diaz-Ordaz, Ruth Keogh, Stephen J W Evans, Liam Smeeth, Alex J Walker
Comparison of methods for predicting COVID-19-related death in the general population using the OpenSAFELY platform. Diagnostic and prognostic research 6 (1) (2022)
Krishnan Bhaskaran, Christopher T Rentsch, George Hickman, William J Hulme, Anna Schultze, Helen J Curtis, Kevin Wing, Charlotte Warren-Gash, Laurie A Tomlinson, Christopher Bates, Rohini Mathur, Brian Mackenna, Viyaasan Mahalingasivam, Angel Yun Wong, Alex J Walker, Caroline E Morton, Daniel J Grint, Amir Mehrkar, Rosalind M M Eggo, Peter Inglesby, Ian J Douglas, Helen I McDonald, Jonathan Cockburn, Elizabeth J Williamson, David Evans, John Parry, Frank Hester, Sam Harper, Stephen Jw Evans, Sebastian C J Bacon, Liam Smeeth, Alex J Walker
Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform. PLoS medicine 19 (1) (2022)
null null, Helen J Curtis, Brian Mackenna, Alex J Walker, Richard Croker, Amir Mehrkar, Caroline E Morton, Sebastian C J Bacon, George Hickman, Peter Inglesby, Christopher Bates, David Evans, Tom Ward, Jonathan Cockburn, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Elizabeth Williamson, William J Hulme, Laurie A Tomlinson, Rohini Mathur, Henry Drysdale, Rosalind M M Eggo, Angel Yun Wong, Harriet J Forbes, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Liam Smeeth, Alex J Walker
OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic. Open heart 8 (2) (2021)
Harriet Forbes, Caroline E Morton, Seb Bacon, Helen I McDonald, Caroline Minassian, Jeremy P Brown, Christopher T Rentsch, Rohini Mathur, Anna Schultze, Nicholas J DeVito, Brian MacKenna, William J Hulme, Richard Croker, Alex J Walker, Elizabeth J Williamson, Chris Bates, Amir Mehrkar, Helen J Curtis, David Evans, Kevin Wing, Peter Inglesby, Henry Drysdale, Angel Y S Wong, Jonathan Cockburn, Robert McManus, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Liam Smeeth, Stephen J W Evans, Krishnan Bhaskaran, Rosalind M Eggo, Alex J Walker, Laurie A Tomlinson
Association between living with children and outcomes from covid-19: OpenSAFELY cohort study of 12 million adults in England. BMJ (Clinical research ed.) 372 (2021)
Helen J Curtis, Seb Bacon, Richard Croker, Alex J Walker, Rafael Perera, Michael Hallsworth, Hugo Harper, Kamal R Mahtani, Carl Heneghan, Alex J Walker
Evaluating the impact of a very low-cost intervention to increase practices' engagement with data and change prescribing behaviour: a randomized trial in English primary care. Family practice 38 (4) (2021)
Samantha A Hollingworth, Georgia C Richards, Brian Mackenna, Alex J Walker
Harnessing medicines data at low cost to deliver better and safer care. Pharmacoepidemiology and drug safety 30 (12) (2021)
Elizabeth J Williamson, Helen I McDonald, Krishnan Bhaskaran, Alex J Walker, Sebastian Bacon, Simon Davy, Anna Schultze, Laurie Tomlinson, Chris Bates, Mary Ramsay, Helen J Curtis, Harriet Forbes, Kevin Wing, Caroline Minassian, John Tazare, Caroline E Morton, Emily Nightingale, Amir Mehrkar, Dave Evans, Peter Inglesby, Brian MacKenna, Jonathan Cockburn, Christopher T Rentsch, Rohini Mathur, Angel Y S Wong, Rosalind M Eggo, William Hulme, Richard Croker, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Stephen J W Evans, Liam Smeeth, Alex J Walker, Hannah Kuper
Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform. BMJ (Clinical research ed.) 374 (2021)
Emily Herrett, Elizabeth J Williamson, Kieran Brack, Alexander D Perkins, Andrew Thayne, Haleema Shakur-Still, Ian Roberts, Danielle Prowse, Danielle Beaumont, Zahra Jamal, Alex J Walker, Tjeerd Pieter van Staa, Thomas M MacDonald, Jane Armitage, Michael V Moore, Maurice Hoffman, Liam Smeeth
The effect of statins on muscle symptoms in primary care: the StatinWISE series of 200 N-of-1 RCTs. Health technology assessment (Winchester, England) 25 (16) (2021)
Emily Herrett, Elizabeth J Williamson, Kieran Brack, Danielle Beaumont, Alexander D Perkins, Andrew Thayne, Haleema Shakur-Still, Ian Roberts, Danielle Prowse, Alex J Walker, Tjeerd Pieter van Staa, Thomas M MacDonald, Jane Armitage, Jon Wimborne, Paula Melrose, Jayshireen Singh, Lucy Brooks, Michael V Moore, Maurice Hoffman, Liam Smeeth, null null
Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials. BMJ (Clinical research ed.) 372 (2021)
Sebastian C J Bacon, Alex J Walker
Barriers to Working With National Health Service England's Open Data. Journal of medical Internet research 22 (1) (2020)
Brian Mackenna, Sebastian C J Bacon, Alex J Walker, Helen J Curtis, Richard Croker, Alex J Walker
Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care. Journal of medical Internet research 22 (10) (2020)
Elizabeth J Williamson, Alex J Walker, Krishnan Bhaskaran, Seb Bacon, Christopher Bates, Caroline E Morton, Helen J Curtis, Amir Mehrkar, David Evans, Peter Inglesby, Jonathan Cockburn, Helen I McDonald, Brian MacKenna, Laurie A Tomlinson, Ian J Douglas, Christopher T Rentsch, Rohini Mathur, Angel Y S Wong, Richard Grieve, David A Harrison, Harriet Forbes, Anna Schultze, Richard Croker, John Parry, Frank Hester, Sam Harper, Rafael Perera, Stephen J W Evans, Liam Smeeth, Alex J Walker
Factors associated with COVID-19-related death using OpenSAFELY. Nature 584 (7821) (2020)
Alex J Walker, Helen J Curtis, Richard Croker, Sebastian C J Bacon, Alex J Walker
Measuring the Impact of an Open Web-Based Prescribing Data Analysis Service on Clinical Practice: Cohort Study on NHS England Data. Journal of medical Internet research 21 (1) (2019)
Alex J Walker, Henry Drysdale, Cicely Marston, Kamal R Mahtani, Aaron Dale, Ioan Milosevic, Eirion Slade, Philip Hartley, Carl Heneghan
COMPare: Qualitative analysis of researchers' responses to critical correspondence on a cohort of 58 misreported trials. Trials 20 (1) (2019)
Alex J Walker, Henry Drysdale, Aaron Dale, Ioan Milosevic, Eirion Slade, Philip Hartley, Cicely Marston, Anna Powell-Smith, Carl Heneghan, Kamal R Mahtani
COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time. Trials 20 (1) (2019)
Alex J Walker, Felix Pretis, Anna Powell-Smith, Ben Goldacre
Variation in responsiveness to warranted behaviour change among NHS clinicians: novel implementation of change detection methods in longitudinal prescribing data. BMJ (Clinical research ed.) 367 (2019)
Jessica Fleminger, Alex J Walker
Prevalence of clinical trial status discrepancies: A cross-sectional study of 10,492 trials registered on both ClinicalTrials.gov and the European Union Clinical Trials Register. PloS one 13 (3) (2018)
Helen J Curtis, John M Dennis, Beverley M Shields, Alex J Walker, Seb Bacon, Andrew T Hattersley, Angus G Jones, Alex J Walker
Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017. Diabetes, obesity & metabolism 20 (9) (2018)
Alex J Walker, Nicholas J DeVito, Carl Heneghan, Francis Irving, Seb Bacon, Jessica Fleminger, Helen Curtis
Compliance with requirement to report results on the EU Clinical Trials Register: cohort study and web resource. BMJ (Clinical research ed.) 362 (2018)
Alex J Walker, Seb Bacon, Richard Croker, Alex J Walker
Detecting change in comparison to peers in NHS prescribing data: a novel application of cumulative sum methodology. BMC medical informatics and decision making 18 (1) (2018)
Alex J Walker, Jonathan Gray
OpenTrials: towards a collaborative open database of all available information on all clinical trials. Trials 17 (2016)