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Evaluation of novel oral polio vaccine type 2 SIA impact in a large outbreak of circulating vaccine-derived poliovirus in Nigeria.

Arend VoormanHil LyonsFaisal ShuabUsman S AdamuCharles KorirTesfaye ErbetoAnanda Sankar BandyopadhyaySamuel Okiror
Published in: The Journal of infectious diseases (2023)
These results are consistent with the comparable individual immunogenicity of nOPV2 and mOPV2 found in clinical trials, but also suggest that outbreak response campaigns may have small impacts in some areas requiring more campaigns than are suggested in current outbreak response procedures.
Keyphrases
  • clinical trial
  • randomized controlled trial
  • open label
  • phase iii