DNA methylation patterns of β-globin cluster in β-thalassemia patients.

Xiuqin BaoYangjin ZuoDiyu ChenCunyou Zhao

Published in: Clinical epigenetics (2020)

Our findings revealed methylation patterns in β-globin cluster associated with β0 thalassemia disease and γ-globin expression, contributed to understand the epigenetic modification in β0 thalassemia patients and provided candidate targets for the therapies of β-hemoglobinopathies.

Keyphrases

dna methylation
end stage renal disease
newly diagnosed
chronic kidney disease
gene expression
prognostic factors
genome wide
poor prognosis
patient reported