Age-associated genes in human mammary gland drive human breast cancer progression.

Xiang GuBingzhi WangHaiyan ZhuYou ZhouAaron M HorningTim H-M HuangYidong ChenPeter HoughtonZhao LaiJoel E MichalekLu-Zhe Sun

Published in: Breast cancer research : BCR (2020)

Our study suggests that transcriptome alterations during aging may contribute to breast tumorigenesis. DYNLT3, P4HA3, and ALX4 play significant roles in breast cancer progression.

Keyphrases

endothelial cells
induced pluripotent stem cells
genome wide
pluripotent stem cells
gene expression
single cell
dna methylation