A 3' tRNA-derived fragment produced by tRNALeuAAG and tRNALeuTAG is associated with poor prognosis in B-cell chronic lymphocytic leukemia, independently of classical prognostic factors.
Katerina KatsarakiPanagiotis G AdamopoulosSotirios G PapageorgiouVassiliki PappaAndreas ScorilasChristos K KontosPublished in: European journal of haematology (2021)
Our approach revealed the independent prognostic value of a particular 3' tRF, derived from tRNALeuAAG and tRNALeuTAG (tRF-LeuAAG/TAG ) in B-CLL.