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A 3' tRNA-derived fragment produced by tRNALeuAAG and tRNALeuTAG is associated with poor prognosis in B-cell chronic lymphocytic leukemia, independently of classical prognostic factors.

Katerina KatsarakiPanagiotis G AdamopoulosSotirios G PapageorgiouVassiliki PappaAndreas ScorilasChristos K Kontos
Published in: European journal of haematology (2021)
Our approach revealed the independent prognostic value of a particular 3' tRF, derived from tRNALeuAAG and tRNALeuTAG (tRF-LeuAAG/TAG ) in B-CLL.
Keyphrases
  • chronic lymphocytic leukemia
  • poor prognosis
  • prognostic factors
  • long non coding rna
  • single cell