Bariatric Surgery and New-Onset Substance Use Disorders: A Systematic review and Meta-analysis.
Silvia MartinelliNiccolo' PetruccianiLuca RegazziMaria Rosaria GualanoPublished in: Obesity surgery (2024)
Increasing evidence suggests that bariatric surgery (BS) patients are at risk for substance abuse disorders (SUD). The purpose of this systematic review and meta-analysis was to determine the relationship between BS and the development of new-onset substance abuse disorder (SUDNO) in bariatric patients. On October 31, 2023, we reviewed the scientific literature following PRISMA guidelines. A total of 3242 studies were analyzed, 7 met the inclusion criteria. The pooled incidence of SUDNO was 4.28%. Patients' characteristics associated with SUDNO included preoperative mental disorders, high pre-BS BMI, and public health insurance. Surgical factors associated with new SUDNOs included severe complications in the peri- or postoperative period. The occurrence of SUDNOs is a non-negligeable complication after BS. Predisposing factors may be identified and preventive actions undertaken.
Keyphrases
- end stage renal disease
- bariatric surgery
- ejection fraction
- health insurance
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- systematic review
- emergency department
- patient reported outcomes
- clinical trial
- open label
- physical activity
- study protocol
- tyrosine kinase
- intimate partner violence
- phase iii