Comparative effect of platelet- and mesenchymal stromal cell-derived extracellular vesicles on human cartilage explants using an ex vivo inflammatory osteoarthritis model.
Maria A Forteza-GenestraMiquel Antich-RossellóGuillem RamisJavier Calvo BenitoAntoni Gayà PuigMarta MonjoJoana Maria RamisPublished in: Bone & joint research (2023)
In conclusion, pEVs showed better performance than cEVs in our in vitro OA model. Although further studies are needed, pEVs are shown as a potential alternative to cEVs for cell-free regenerative medicine.