Login / Signup

One-carbon cycle support rescues sperm damage in experimentally induced varicocoele in rats.

Parisa MohammadiHassan Hassani-BafraniMarziyeh TavalaeeMaurizio DattiloMohammad H Nasr-Esfahani
Published in: BJU international (2018)
Micronutrients in support of the one-carbon cycle are effective in the treatment of surgically induced varicocoele in rats, probably by activating natural antioxidant defences and epigenetics. These results support the idea that essential micronutrients including B vitamins may also have a positive influence in clinical varicocoele, which should be tested in prospective clinical trials.
Keyphrases
  • clinical trial
  • high glucose
  • diabetic rats
  • oxidative stress
  • randomized controlled trial
  • endothelial cells
  • mouse model
  • open label
  • phase ii