Triglyceride profiling in adipose tissues from obese insulin sensitive, insulin resistant and type 2 diabetes mellitus individuals.

Haya Al-SulaitiIlhame DibounSameem BanuMohamed Al-EmadiParvaneh AmaniThomas M HarveyAlex S DömlingAishah LatiffMohamed A Elrayess

Published in: Journal of translational medicine (2018)

Pilot data suggest that adipose tissues from obese IR and T2DM individuals exhibit TAG-specific signatures that may contribute to their increased risk compared to their IS counterparts. Future experiments are warranted to investigate the functional relevance of these specific lipidomic profiles.

Keyphrases

type diabetes
glycemic control
adipose tissue
weight loss
insulin resistance
metabolic syndrome
gene expression
obese patients
randomized controlled trial
machine learning
single cell
big data
dna methylation
clinical trial
double blind