Low P4HA2 and high PRTN3 expression predicts poor survival in patients with pancreatic cancer.
Dingyuan HuDaniel AnsariQimin ZhouAgata SasorKatarzyna Said HilmerssonRoland AnderssonPublished in: Scandinavian journal of gastroenterology (2019)
Our data show that a low P4HA2 and high PRTN3 expression correlates with poor survival in patients with pancreatic cancer, indicating the involvement of collagen deposition in the restraint of the tumor. The tumoral expression of PRTN3 reinforces the therapeutic potential of PR1-targeting immunotherapy in pancreatic cancer.