Genetic Profiling in Children With Acute Lymphoblastic Leukemia Referred for Allogeneic Hematopoietic Stem Cell Transplantation.

Kinga KwiecinskaWojciech StrojnyMiroslaw Bik-Multanowskinull Michal KorostynskiMarcin PiechotaWalentyna BalwierzSzymon Skoczeń

Published in: Cancer control : journal of the Moffitt Cancer Center (2022)

Genome expression of patients with ALL in remission referred to HSCT revealed deep immunosuppression of both B-cell and T-cell lineages, which may increase the probability of donor cell engraftment.

Keyphrases

allogeneic hematopoietic stem cell transplantation
acute lymphoblastic leukemia
single cell
acute myeloid leukemia
genome wide
poor prognosis
hematopoietic stem cell
young adults
cell therapy
disease activity
copy number
stem cells
dna methylation