Vedolizumab for treatment of chronic refractory pouchitis: a systematic review with pool analysis.

Davide Giuseppe Ribaldone Rinaldo Pellicano Giorgio Maria Saracco Mario Morino Marco Astegiano

Published in: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva (2021)

this first systematic review published in the literature on this issue suggests that vedolizumab has significant efficacy in chronic refractory or antibiotic-dependent pouchitis, also in patients who failed to respond to other treatments including those with anti-TNF agents.

Keyphrases

systematic review
ulcerative colitis
meta analyses
patients with inflammatory bowel disease
randomized controlled trial
replacement therapy