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Longitudinal development of thalamic and internal capsule microstructure in autism spectrum disorder.

Kristine McLaughlinBrittany G TraversOlga I DadalkoDouglas C DeanDo TrompNagesh AdluruDaniel DesticheAbigail FreemanMolly D PriggeAlyson FroehlichTyler C DuffieldBrandon A ZielinskiErin D BiglerNicholas LangeJeff S AndersonAndrew L AlexanderJanet E Lainhart
Published in: Autism research : official journal of the International Society for Autism Research (2017)
Microstructure of the thalamus, a key sensory and motor brain area, appears to develop differently in individuals with autism spectrum disorder (ASD). Microstructure is important because it informs us of the density and organization of different brain tissues. During childhood, thalamic microstructure was distinct in the ASD group compared to the typically developing group. However, these group differences appeared to narrow with age, suggesting that the thalamus continues to dynamically change in ASD into adulthood.
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