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Imaging and clinical manifestations of immune checkpoint inhibitor-related colitis in cancer patients treated with monotherapy or combination therapy.

Alice C ShiehEzgi GulerDavid PfauEthan RadzinskyDaniel A SmithChristopher HoimesNikhil H RamaiyaSree Harsha Tirumani
Published in: Abdominal radiology (New York) (2021)
Immune-related colitis occurred in 3.3% of patients receiving ICIs with bowel wall thickening, fluid-filled colon and pancolitis being the most common imaging manifestations. Imaging manifestations did not differ between patients receiving monotherapy or combination therapy. However, concurrent irAEs were significantly observed in patients undergoing combination therapy.
Keyphrases
  • combination therapy
  • high resolution
  • patients undergoing
  • randomized controlled trial
  • clinical trial
  • ulcerative colitis
  • mass spectrometry
  • study protocol