Selenium deficiency induces spleen pathological changes in pigs by decreasing selenoprotein expression, evoking oxidative stress, and activating inflammation and apoptosis.

Shuang LiWenjuan SunKai ZhangJiawei ZhuXueting JiaXiaoqing GuoQingyu ZhaoChaohua TangJingdong YinJunmin Zhang

Published in: Journal of animal science and biotechnology (2021)

These results indicated that Se deficiency induces spleen injury through the regulation of selenoproteins, oxidative stress, inflammation and apoptosis.

Keyphrases

oxidative stress
diabetic rats
dna damage
ischemia reperfusion injury
induced apoptosis
poor prognosis
signaling pathway
replacement therapy
endoplasmic reticulum stress
cell death