Developments in high-throughput functional epigenomics: CRISPR-single-cell assay for transposase-accessible chromatin using sequencing screens.

Rachel E YanJeffrey P GreenfieldNadia Dahmane

Published in: Epigenomics (2022)

Tweetable abstract CRISPR-scATAC-seq screens pave the way for high-throughput functional epigenomics by linking perturbations to a broad view of epigenetic state and messages hidden within accessible sequences.

Keyphrases

high throughput
single cell
genome wide
rna seq
dna methylation
genome editing
crispr cas
gene expression
dna damage
oxidative stress