Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model.

Darragh P O'BrienAdam M ThorneHonglei HuangElisa PappalardoXuan YaoPeter Søndergaard ThyrrestrupKristian RavloNiels SecherRikke NorregaardRutger J PloegBente JespersenBenedikt Mathias Kessler

Published in: Clinical proteomics (2022)

Our data identifies subtle molecular phenotypes in porcine kidneys following RIC, and this knowledge could potentially aid optimization of remote ischemic conditioning protocols in renal transplantation.

Keyphrases

ischemia reperfusion injury
healthcare
single molecule
genome wide
single cell
big data
gene expression
oxidative stress
machine learning
artificial intelligence
data analysis
blood brain barrier