TB-PRACTECAL: study protocol for a randomised, controlled, open-label, phase II-III trial to evaluate the safety and efficacy of regimens containing bedaquiline and pretomanid for the treatment of adult patients with pulmonary multidrug-resistant tuberculosis.
Catherine BerryPhilipp du CrosKatherine FieldingSuzanne GajewskiEmil KazounisTimothy D McHughCorinne MerleIlaria MottaDavid A J MooreBern-Thomas Nyang'waPublished in: Trials (2022)
Clinicaltrials.gov NCT02589782. Registered on 28 October 2015.
Keyphrases
- phase ii
- open label
- multidrug resistant
- clinical trial
- phase iii
- study protocol
- drug resistant
- mycobacterium tuberculosis
- acinetobacter baumannii
- gram negative
- phase ii study
- placebo controlled
- pulmonary hypertension
- double blind
- randomized controlled trial
- klebsiella pneumoniae
- pulmonary tuberculosis
- hiv aids
- combination therapy
- cystic fibrosis
- hepatitis c virus
- escherichia coli
- replacement therapy
- smoking cessation