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Comparison of the therapeutic effects of erythropoietin and acetyl-l-carnitine on sciatic nerve injury in rats.

Ceren Kencebay ManasNarin DerinRamazan Yavuz AricanGamze TanriÖverSayra DİlmaÇHaluk Özcanli
Published in: Neurological research (2022)
EPO and ALCAR administration could accelerate sciatic nerve repair by reducing apoptosis and lipid peroxidation and promoting myelinization. Although both EPO and ALCAR had positive effects on nerve healing, their combined efficacy had no statistically significant effect on peripheral nerve regeneration.
Keyphrases
  • peripheral nerve
  • stem cells
  • oxidative stress
  • endoplasmic reticulum stress
  • cell cycle arrest
  • cell death
  • fatty acid
  • recombinant human
  • wound healing