Low-dose naltrexone and opioid consumption: a drug utilization cohort study based on data from the Norwegian prescription database.

Published in: Pharmacoepidemiology and drug safety (2017)

Possibly, LDN users avoided opioids because of warnings on concomitant use or the patients continuing on LDN were less opioid dependent than those terminating LDN. Therapeutic effects of LDN contributing to lower opioid consumption cannot be ruled out. © 2017 The Authors. Pharmacoepidemiology & Drug Safety Published by John Wiley & Sons Ltd.

Keyphrases

chronic pain
pain management
low dose
end stage renal disease
chronic kidney disease
ejection fraction
adverse drug
newly diagnosed
randomized controlled trial
peritoneal dialysis
emergency department
prognostic factors
electronic health record
systematic review
drug induced
machine learning
data analysis