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Comparing the effect of benzoic acid and cinnamic acid hydroxyl derivatives on polyphenol oxidase: activity, action mechanism, and molecular docking.

Yuefang SunLei ZhouTao LiaoJunping LiuKaibo YuLiqiang ZouWei ZhouWei Liu
Published in: Journal of the science of food and agriculture (2022)
Comparative analysis showed that the inhibition effect of cinnamic acid hydroxyl derivatives on PPO was stronger than that of benzoic acid derivatives. Benzoic acid and 2,4-dihydroxycinnamic acid were the strongest inhibitors. PPO inhibitors identified from benzoic and cinnamic acid derivatives are expected to be promising inhibitors for controlling fruit and vegetable browning. © 2021 Society of Chemical Industry.
Keyphrases
  • molecular docking
  • type diabetes
  • skeletal muscle
  • molecular dynamics simulations
  • structure activity relationship