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Cytotoxicity and antimicrobial activity of synthetic peptides alone or in combination with conventional antimicrobials against fish pathogenic bacteria.

Inácio Mateus AssaneNorival Alves Santos-FilhoE L de SousaM C O de Arruda BrasilEduardo Maffud CilliFabiana Pilarski
Published in: Journal of applied microbiology (2021)
The in vivo effectiveness of synthetic HDPs such as KR-12-a5; LL-37; (p-BthTX-I)2 and Hylin a1 can be tested alone or in combination with conventional antimicrobials as a treatment option to reduce the use of antimicrobials in aquaculture.
Keyphrases
  • randomized controlled trial
  • combination therapy
  • amino acid
  • replacement therapy