The augmentation of cytotoxic immune cell functionality through physical exertion bolsters the potency of chemotherapy in models of mammary carcinoma.

Bingqing QinZhongshi HeLixia XieShenglan FengJunjie YeJianjun GuiXiaodong Sun Ming Sang

Published in: Cancer medicine (2024)

Physical training improves the effectiveness of doxorubicin in treating breast cancer by activating cytotoxic immune cells, releasing tumor suppressor factors, and initiating mt-apoptosis, all while mitigating the adverse effects of chemotherapy.

Keyphrases

physical activity
locally advanced
mental health
randomized controlled trial
oxidative stress
endoplasmic reticulum stress
systematic review
signaling pathway
drug delivery
cell death
chemotherapy induced
rectal cancer
childhood cancer