Evaluation of the one-step nucleic acid amplification method for rapid detection of lymph node metastases in endometrial cancer: prospective, multicenter, comparative study.
Eleonora La FeraNicolò BizzarriAlessandro PetreccaGiorgia MonterossiGiorgia DinoiGian Franco ZannoniStefano RestainoEmilia PalmieriLaura MariuzziInge PetersGiovanni ScambiaFrancesco FanfaniPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2023)
The OSNA method had high specificity and high accuracy in detecting SLN metastasis in apparent early-stage endometrial cancer. The advantage of the OSNA method could be represented as the possibility to analyze the entire lymph node thus eliminating sampling bias.