Dysregulation of FTX/miR-545 signaling pathway downregulates Tim-3 and is responsible for the abnormal activation of macrophage in cirrhosis.

Xia LiuCong LiJie ZhuWenshuai LiQiang Zhu

Published in: Journal of cellular biochemistry (2018)

The results of this study confirmed the effect of FTX, miR-545, and Tim-3 on the expression of inflammatory cytokines, the lymphocyte/monocyte ratio, and the severity and prognosis of HBV-related cirrhosis.

Keyphrases

long non coding rna
cell proliferation
poor prognosis
signaling pathway
long noncoding rna
peripheral blood
hepatitis b virus
pi k akt
dendritic cells
adipose tissue
endothelial cells
immune response
binding protein
liver failure
endoplasmic reticulum stress
induced apoptosis