Zinc finger protein 468 up-regulation of TFAM contributes to the malignant growth and cisplatin resistance of breast cancer cells.
Zhaoyang JiaFeng WangGongzhuo LiPing JiangYuanxiu LengLongzhu KeLi LuoWei Gao
Published in: Cell division (2024)
Our study indicates that ZNF468 promotes BC cell growth and migration via transcriptional activation of TFAM. ZNF468/TFAM axis can serve as the diagnostic and therapeutic target, as well as the predictor of cisplatin effectiveness in BC patients.