Diffuse PRAME Expression Is Highly Specific for Thin Melanomas in the Distinction from Severely Dysplastic Nevi but Does Not Distinguish Metastasizing from Non-Metastasizing Thin Melanomas.
Maximilian GassenmaierMatthias HahnGisela MetzlerJürgen BauerAmir Sadegh YazdiUlrike KeimClaus GarbeNikolaus Benjamin WagnerStephan ForchhammerPublished in: Cancers (2021)
Diffuse intraepidermal and dermal PRAME staining is highly specific for melanomas in the distinction from SDN. PRAME expression is not a prognostic biomarker in melanomas ≤1.0 mm.