Vasopressin Analog [V 4 Q 5 ]dDAVP Exerts Cooperative Anticancer Effects in Combination With Low-Dose 5-Fluorouracil on Aggressive Colorectal Cancer Models.

Natasha T SobolLuisina M SolernoCandela LlavonaDaniel Fernando Alonso Juan Garona

Published in: World journal of oncology (2023)

]dDAVP seems to enhance the efficacy of 5-FU-based chemotherapy in CRC by modulating tumor progression, as well as metastatic dissemination, suggesting its potential role as a safe and cost-effective co-adjuvant agent for the management of advanced CRC.

Keyphrases

low dose
squamous cell carcinoma
small cell lung cancer
poor prognosis
early stage
high dose
signaling pathway
locally advanced
rectal cancer