The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver.
Paulina KurAgnieszka Kinga KolasaMarta GrabowskaAndrzej KramArkadiusz TelesińskiIrena Baranowska-BosiackaSylwia RzeszotekMalgorzata PiaseckaBarbara WiszniewskaPublished in: International journal of molecular sciences (2021)
It seems that treating male adult rats with finasteride causes changes in the carbohydrate metabolism in the liver of their offspring. This can lead to improper hepatic energy homeostasis or even hyperglycaemia, insulin resistance, as well as some symptoms of metabolic syndrome and liver steatosis.