Hypoxemia events in preterm neonates are associated with urine oxidative biomarkers.
Thomas M RaffayJuliann M Di FioreZhengyi ChenÁngel Sánchez-IllanaMaximo VentoJosé David Piñeiro-RamosJulia KuligowskiRichard J MartinCurtis TatsuokaNori M MinichPeter M MacFarlaneAnna Maria HibbsPublished in: Pediatric research (2023)
Hypoxemia events are frequent in preterm infants and are associated with poor outcomes. The mechanisms by which hypoxemia events result in adverse neural and respiratory outcomes may include oxidative stress to lipids, proteins, and DNA. This study begins to explore associations between hypoxemia parameters and products of oxidative stress in preterm infants. Oxidative stress biomarkers may assist in identifying high-risk neonates.