Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Severe Traumatic Brain Injury.
Bradley A DenglerOliver KaramColleen A BartholAaron ChanceLaura E SniderClare M MundyMichael T BounajemWilliam C JohnsonMoustafa M MaitaPaola M Mendez-GomezAli SeifiShaheryar HafeezPublished in: Critical care research and practice (2022)
In this single-institution study of patients with severe traumatic brain injury, ketamine boluses were associated with a reduction in ICP and an increase in CPP. This was a retrospective review of 43 patients and is therefore limited in nature, but further randomized controlled trials should be performed to confirm the findings.
Keyphrases
- severe traumatic brain injury
- traumatic brain injury
- end stage renal disease
- randomized controlled trial
- newly diagnosed
- ejection fraction
- chronic kidney disease
- pain management
- prognostic factors
- subarachnoid hemorrhage
- peritoneal dialysis
- patient reported outcomes
- study protocol
- magnetic resonance
- patient reported
- meta analyses