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Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies.

L L N HusemoenT SkaabyB H ThuesenNiels GrarupC H SandholtT HansenO PedersenAllan Linneberg
Published in: European journal of clinical nutrition (2016)
GRSs were not associated with blood pressure and lipid levels, except for an association between the GRS for folate and HDL cholesterol. Further studies are needed to determine whether a causal association between folate and HDL cholesterol exists.
Keyphrases
  • blood pressure
  • hypertensive patients
  • low density lipoprotein
  • blood glucose
  • case control
  • fatty acid
  • insulin resistance
  • genome wide
  • type diabetes
  • gene expression
  • adipose tissue
  • metabolic syndrome
  • weight loss