The intervention on aging system: A classification model, the requirement for five novel categories.
Raymond D PalmerPublished in: Aging medicine (Milton (N.S.W)) (2022)
Aging is widely considered an immovable fact of life. Cultural conditioning has ensured that therapeutics for extreme human lifespans are considered out of reach technologies. However, longevity therapies such as stem cell replacement, fasting, gene therapies, fasting mimetics such as metformin and rapamycin, regulation and tissue reprogramming with OSK transcription factors, blood dilution, metabolic pathway engineering, reversal of epigenetic drift, heterochronic parabiosis, coenzyme replacement technologies (nicotinamide adenine dinucleotide) and a plethora of other established sciences are showing great potential at slowing down the rate at which tissues enter dysfunction. Recent discoveries have shed light on major mysteries of the aging process. Longevity-based discoveries are not only landing quickly, but therapies to prevent or reverse those drivers of aging are also being devised regularly and this is opening up an entirely new industry, the longevity industry. This presents the requirement for a new classification system where subjects can be divided into specific groups based on their potential for mortality. This system also enables the public to target which class of this classification system they wish to be on. Moving the population on the classification system to become more disease resistant holds great benefit for society and governments as a whole.
Keyphrases
- stem cells
- transcription factor
- gene expression
- randomized controlled trial
- healthcare
- blood glucose
- insulin resistance
- drosophila melanogaster
- endothelial cells
- dna methylation
- machine learning
- climate change
- mental health
- small molecule
- copy number
- genome wide
- metabolic syndrome
- liquid chromatography tandem mass spectrometry
- genome wide identification
- cardiovascular disease
- mass spectrometry
- adverse drug
- ms ms
- mesenchymal stem cells
- cell therapy
- simultaneous determination
- tandem mass spectrometry