Wnt Signaling Interactor WTIP (Wilms Tumor Interacting Protein) Underlies Novel Mechanism for Cardiac Hypertrophy.
Hannah N De JongFrederick E DeweyPablo CorderoRachelle A VictorioAnna KirillovaYong HuangRoshni MadhvaniKinya SeoFeng LanMark OrcholskiW Robert LiuAyca ErbilginMatthew T WheelerRui ChenStephen PanYoung M KimKrishna BommakantiCherisse A MarcouJ Martijn BosFrancois HaddadMichael J AckermanRamachandran S VasanCalum A MacRaeJoseph C WuVinicio A de Jesus PerezMichael Paul SnyderVictoria N ParikhEuan A AshleyPublished in: Circulation. Genomic and precision medicine (2022)
is important in complex cardiac hypertrophy phenotypes. These findings, derived from the observation of a rare Mendelian disease variant, uncover a novel disease mechanism with implications across diverse forms of cardiac hypertrophy.
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