Exploring Genetic Drug Targets in Acne Vulgaris: A Comprehensive Proteome-Wide Mendelian Randomization Study.

Ruyi JuYuou YingQiujun ZhouYi Cao

Published in: Journal of cosmetic dermatology (2024)

Our findings highlight the utility of integrative genomic approaches in identifying potential therapeutic targets for acne. FASN and TIMP4, in particular, demonstrate strong potential as targets for therapeutic intervention, pending further validation through clinical research. These results offer a foundation for targeted acne treatment development, aligning with personalized medicine principles.

Keyphrases

hidradenitis suppurativa
randomized controlled trial
copy number
genome wide
cancer therapy
emergency department
gene expression
drug delivery
risk assessment
dna methylation
smoking cessation
clinical evaluation