Inhibition of renal fibrosis with a human CXCL9-derived glycosaminoglycan-binding peptide.
Fariba PoostiMohammad Ayodhia SoebadiHelena CrijnsAlexandra De ZutterMieke MetzemaekersNele BerghmansVincent VanheuleMaarten AlbersenGhislain OpdenakkerJo Van DammeBen SprangersMieke GouwySofie StruyfPublished in: Clinical & translational immunology (2022)
Our findings provide a scientific rationale for targeting GAG-protein interactions in renal fibrotic disease.