Dysregulated carbohydrate and lipid metabolism and risk of atrial fibrillation in advanced old age.
Cara N PellegriniPetra BuzkovaAdam OesterleSusan R HeckbertRussell P TracyDavid S SiscovickKenneth J MukamalLuc DjousséJorge R KizerPublished in: Heart (British Cardiac Society) (2022)
Among older adults, postload glucose was positively associated with incident AF, with consistent findings for PTFV1. In exploratory analyses, the relationship with AF appeared specific to women. These findings require further study but suggest that interventions to address postprandial dysglycaemia late in life might reduce AF.
Keyphrases
- atrial fibrillation
- oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- direct oral anticoagulants
- blood glucose
- heart failure
- percutaneous coronary intervention
- physical activity
- cardiovascular disease
- polycystic ovary syndrome
- type diabetes
- adipose tissue
- fatty acid
- coronary artery disease
- acute coronary syndrome
- mitral valve
- skeletal muscle
- pregnancy outcomes
- left ventricular
- glycemic control