The relationship of mental health symptoms to chemotherapy toxicity risk in older adults with cancer: Results from the geriatric assessment-driven intervention study.
Reena V JayaniAnahid HamparsumianCanlan SunDaneng LiLeana Cabrera ChienJeanine MorenoVani KatheriaSimone Fernandes Dos Santos HughesWarren D TaylorWilliam DalePublished in: Cancer (2024)
Elevated depression symptoms are associated with increased risk of severe CT in older adults with cancer, which was mitigated with GAIN. This suggests that treating depression symptoms may lower toxicity risk. Future studies are needed to confirm and investigate the impact of depression-specific interventions on outcomes.
Keyphrases
- sleep quality
- physical activity
- papillary thyroid
- depressive symptoms
- mental health
- squamous cell
- randomized controlled trial
- computed tomography
- type diabetes
- lymph node metastasis
- squamous cell carcinoma
- childhood cancer
- skeletal muscle
- metabolic syndrome
- young adults
- adipose tissue
- rectal cancer
- dual energy
- case control
- oxide nanoparticles
- drug induced