Multiple Sclerosis Therapy With Disease-Modifying Treatments in Germany: The PEARL (ProspEctive phArmacoeconomic cohoRt evaluation) Noninterventional Study Protocol.
Stefan Viktor VormfeldeSonja OrtlerTjalf ZiemssenPublished in: JMIR research protocols (2016)
PEARL is evaluating both the health status and resource utilization of RRMS patients treated with DMTs in Germany. The combination of pharmacoeconomic data with clinical and patients' self-perceived efficacy and safety outcomes will add useful information to the currently incomplete picture of the overall RRMS burden in Germany.
Keyphrases
- multiple sclerosis
- end stage renal disease
- study protocol
- ejection fraction
- newly diagnosed
- randomized controlled trial
- chronic kidney disease
- clinical trial
- physical activity
- peritoneal dialysis
- prognostic factors
- mental health
- healthcare
- electronic health record
- type diabetes
- stem cells
- big data
- metabolic syndrome
- insulin resistance
- cell therapy
- open label
- patient reported