Lactate Production can Function to Increase Human Epithelial Cell Iron Concentration.
Caroline GhioJoleen M SoukupLisa A DaileyAndrew J GhioDina M SchreinemachersRyan A KoppesAbigail N KoppesPublished in: Cellular and molecular bioengineering (2022)
Therefore, we conclude that iron import in human epithelial cells can involve lactate, LDH activity can reflect the availability of this metal, and blood LDH concentrations can correlate with indices of iron homeostasis.