Increased GH/IGF-I axis activity relates with lower hepatic lipids and phosphor metabolism.
Paul FellingerHannes BeiglböckGeorg SemmlerLorenz PflegerSabina SmajisClemens BaumgartnerMartin GajdosikRodrig MarculescuGreisa VilaYvonne WinhoferThomas SchererMichael TraunerAlexandra Kautzky-WillerMartin KrssakMichael R KrebsPeter WolfPublished in: The Journal of clinical endocrinology and metabolism (2023)
GH/IGF-I axis activity impacts hepatic lipid and phosphate metabolism in individuals without disorders in GH secretion. Lower GH-axis activity is associated with higher IHL and an unfavourable lipid composition, probably mediated by changes in hepatic energy metabolism.