Developing and validating a multivariable prognostic-predictive classifier for treatment escalation of oropharyngeal squamous cell carcinoma: the PREDICTR-OPC study.

Hisham Mehanna Davy Rapozo Sandra Lucia Ventorin Von Zeidler Kevin J Harrington Stuart C Winter Andrew Hartley Paul Nankivell Andrew Graeme Schache Philip Sloan Edward William Odell Selvam Thavaraj Keith David Hunter Ketan A Shah Gareth J Thomas Anna Long Rasoul Amel-Kashipaz Rachel M Brown Brendan Conn Gillian L Hall Paul Matthews Justin Weir Yen Yeo Miranda Pring Catharine M L West James McCaul Paweł Golusinski Alice J Sitch Rachel Spruce Nikolaos Batis Jennifer L Bryant Jill M Brooks Terence M Jones Francesca M Buffa Syed Haider Max Robinson

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

We have developed a prognostic classifier, which also appears to demonstrate moderate predictive ability. External validation in a prospective setting is now underway to confirm this and prepare for clinical adoption.

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