Syed Haider

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 37

Top Venues

British journal of cancer

Clinical cancer research : an official journal of the American Association for Cancer Research

Nature communications

NPJ breast cancer

The Institute of Cancer Research

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The Institute of Cancer Research Nov 15 2016

United Kingdom

Group Leader (Breast Cancer Research Bioinformatics) :: Breast Cancer Division

Ontario Institute for Cancer Research Jan 01 2012 - Oct 01 2016

Canada

Postdoctoral Researcher :: Informatics and Bio-computing

Weatherall Institute of Molecular Medicine, University of Oxford May 01 2013 - Sep 30 2016

United Kingdom

Postdoctoral Researcher :: Oncology

Education History

University of Cambridge Jan 10 2009 - Jan 10 2012

United Kingdom

PHD :: Computing

Publications

Anthony Cheung, Alicia M Chenoweth, Annelie Johansson, Roman Laddach, Naomi Jayne Guppy, Jennifer Trendell, Benjamina Esapa, Antranik Mavousian, Blanca Navarro-Llinas, Syed Haider, Pablo Romero-Clavijo, Ricarda M Hoffmann, Paolo Andriollo, Khondaker Miraz Rahman, Paul Jackson, Sophia Tsoka, Sheeba Irshad, Ioannis Roxanis, Anita Grigoriadis, David E Thurston, Christopher J Lord, Andrew N J Tutt, Sophia N Karagiannis
Anti-EGFR Antibody-Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (15) (2024)
Carlos Ronchi, Syed Haider, Cathrin Brisken
EMBER creates a unified space for independent breast cancer transcriptomic datasets enabling precision oncology. NPJ breast cancer 10 (1) (2024)
John Alexander, Koen Schipper, Sarah Nash, Rachel Brough, Harriet Kemp, Jacopo Iacovacci, Clare M Isacke, Rachael Natrajan, Elinor J Sawyer, Christopher J Lord, Syed Haider
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer. British journal of cancer 130 (11) (2024)
John Alexander, Koen Schipper, Sarah Nash, Rachel Brough, Harriet Kemp, Jacopo Iacovacci, Clare M Isacke, Rachael Natrajan, Elinor J Sawyer, Christopher J Lord, Syed Haider
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer. British journal of cancer 130 (11) (2024)
Anthony Cheung, Alicia M Chenoweth, Annelie Johansson, Roman Laddach, Naomi Jayne Guppy, Jennifer Trendell, Benjamina Esapa, Antranik Mavousian, Blanca Navarro-Llinas, Syed Haider, Pablo Romero-Clavijo, Ricarda M Hoffmann, Paolo Andriollo, Khondaker Miraz Rahman, Paul Jackson, Sophia Tsoka, Sheeba Irshad, Ioannis Roxanis, Anita Grigoriadis, David E Thurston, Christopher J Lord, Andrew N J Tutt, Sophia N Karagiannis
Anti-EGFR antibody-drug conjugate carrying an inhibitor targeting CDK restricts triple-negative breast cancer growth. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
John Alexander, Koen Schipper, Sarah Nash, Rachel Brough, Harriet Kemp, Jacopo Iacovacci, Clare M Isacke, Rachael Natrajan, Elinor J Sawyer, Christopher J Lord, Syed Haider
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer. British journal of cancer (2024)
Anthony Cheung, Alicia M Chenoweth, Annelie Johansson, Roman Laddach, Naomi Jayne Guppy, Jennifer Trendell, Benjamina Esapa, Antranik Mavousian, Blanca Navarro-Llinas, Syed Haider, Pablo Romero-Clavijo, Ricarda M Hoffmann, Paolo Andriollo, Khondaker Miraz Rahman, Paul Jackson, Sophia Tsoka, Sheeba Irshad, Ioannis Roxanis, Anita Grigoriadis, David E Thurston, Christopher J Lord, Andrew N J Tutt, Sophia N Karagiannis
Anti-EGFR Antibody-Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (15) (2024)
Carlos Ronchi, Syed Haider, Cathrin Brisken
EMBER creates a unified space for independent breast cancer transcriptomic datasets enabling precision oncology. NPJ breast cancer 10 (1) (2024)
Carlos Ronchi, Syed Haider, Cathrin Brisken
EMBER creates a unified space for independent breast cancer transcriptomic datasets enabling precision oncology. NPJ breast cancer 10 (1) (2024)
John Alexander, Koen Schipper, Sarah Nash, Rachel Brough, Harriet Kemp, Jacopo Iacovacci, Clare M Isacke, Rachael Natrajan, Elinor J Sawyer, Christopher J Lord, Syed Haider
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer. British journal of cancer 130 (11) (2024)
Anthony Cheung, Alicia M Chenoweth, Annelie Johansson, Roman Laddach, Naomi Jayne Guppy, Jennifer Trendell, Benjamina Esapa, Antranik Mavousian, Blanca Navarro-Llinas, Syed Haider, Pablo Romero-Clavijo, Ricarda M Hoffmann, Paolo Andriollo, Khondaker Miraz Rahman, Paul Jackson, Sophia Tsoka, Sheeba Irshad, Ioannis Roxanis, Anita Grigoriadis, David E Thurston, Christopher J Lord, Andrew N J Tutt, Sophia N Karagiannis
Anti-EGFR Antibody-Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (15) (2024)
Hisham Mehanna, Davy Rapozo, Sandra Lucia Ventorin Von Zeidler, Kevin J Harrington, Stuart C Winter, Andrew Hartley, Paul Nankivell, Andrew Graeme Schache, Philip Sloan, Edward William Odell, Selvam Thavaraj, Keith David Hunter, Ketan A Shah, Gareth J Thomas, Anna Long, Rasoul Amel-Kashipaz, Rachel M Brown, Brendan Conn, Gillian L Hall, Paul Matthews, Justin Weir, Yen Yeo, Miranda Pring, Catharine M L West, James McCaul, Paweł Golusinski, Alice J Sitch, Rachel Spruce, Nikolaos Batis, Jennifer L Bryant, Jill M Brooks, Terence M Jones, Francesca M Buffa, Syed Haider, Max Robinson
Developing and validating a multivariable prognostic-predictive classifier for treatment escalation of oropharyngeal squamous cell carcinoma: the PREDICTR-OPC study. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Amanda Fitzpatrick, Marjan Iravani, Adam Mills, David Vicente, Thanussuyah Alaguthurai, Ioannis Roxanis, Nicholas C Turner, Syed Haider, Andrew N J Tutt, Clare M Isacke
Genomic profiling and pre-clinical modelling of breast cancer leptomeningeal metastasis reveals acquisition of a lobular-like phenotype. Nature communications 14 (1) (2023)
Frances K Turrell, Rebecca Orha, Naomi J Guppy, Andrea Gillespie, Matthew Guelbert, Chris Starling, Syed Haider, Clare M Isacke
Age-associated microenvironmental changes highlight the role of PDGF-C in ER + breast cancer metastatic relapse. Nature cancer (2023)
Arany Soosainathan, Marjan Iravani, Rania El-Botty, John Alexander, Laura Sourd, Ludivine Morisset, Pierre Painsec, Rebecca Orha, Joanna Nikitorowicz-Buniak, Sunil Pancholi, Syed Haider, Mitchell Dowsett, Elisabetta Marangoni, Lesley-Ann Martin, Clare M Isacke
Targeting transcriptional regulation with a CDK9 inhibitor suppresses growth of endocrine- and palbociclib-resistant ER+ breast cancers. Cancer research (2023)
Philip Bland, Harry Saville, Patty T Wai, Lucinda Curnow, Gareth Muirhead, Jadwiga Nieminuszczy, Nivedita Ravindran, Marie Beatrix John, Somaieh Hedayat, Holly E Barker, James Wright, Lu Yu, Ioanna Mavrommati, Abigail Read, Barrie Peck, Mark Allen, Patrycja Gazinska, Helen N Pemberton, Aditi Gulati, Sarah Nash, Farzana Noor, Naomi Guppy, Ioannis Roxanis, Guy Pratt, Ceri E Oldreive, Tatjana Stankovic, Samantha Barlow, Helen Kalirai, Sarah E Coupland, Ronan Broderick, Samar Alsafadi, Alexandre Houy, Marc-Henri Stern, Stephen J Pettitt, Jyoti Sharma Choudhary, Syed Haider, Wojciech Niedzwiedz, Christopher J Lord, Rachael Natrajan
SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response. Nature genetics (2023)
Holly Tovey, Orsolya Sipos, Joel S Parker, Katherine A Hoadley, Jelmar Quist, Sarah Kernaghan, Lucy Suzanne Kilburn, Roberto Salgado, Sherene Loi, Richard D Kennedy, Ioannis Roxanis, Patrycja Gazinska, Sarah E Pinder, Judith M Bliss, Charles M Perou, Syed Haider, Anita Grigoriadis, Andrew N J Tutt, Maggie Chon U Cheang
Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Marta J Llorca-Cardenosa, Lauren I Aronson, Dragomir B Krastev, Jadwiga Nieminuszczy, John Alexander, Feifei Song, Malgorzata Dylewska, Ronan Broderick, Rachel Brough, Astrid Zimmermann, Frank T Zenke, Bora Gurel, Ruth Riisnaes, Ana Ferreira, Theodoros I Roumeliotis, Jyoti Sharma Choudhary, Stephen J Pettitt, Johann S de Bono, Andres Cervantes, Syed Haider, Wojciech Niedzwiedz, Christopher J Lord, Irene Y Chong
SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance. Cancer research 82 (21) (2022)
Christos E Zois, Anne M Hendriks, Syed Haider, Elisabete Pires, Esther Bridges, Dimitra Kalamida, Dimitrios Voukantsis, B Christoffer Lagerholm, Rudolf S N Fehrmann, Wilfred F A den Dunnen, Andrei I Tarasov, Otto Baba, John Morris, Francesca M Buffa, James S O McCullagh, Mathilde Jalving, Adrian L Harris
Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation. Cell death & disease 13 (6) (2022)
Constance H Li, Syed Haider, Paul C Boutros
Age influences on the molecular presentation of tumours. Nature communications 13 (1) (2022)
Patrycja Gazinska, Charlotte K Milton, Jacopo Iacovacci, Joseph A Ward, Richard Buus, Thanussuyah Alaguthurai, Rosalind Graham, Ayse U Akarca, Esther H Lips, Kalnisha Naidoo, Jelle Wesseling, Teresa Marafioti, Maggie Chon U Cheang, Cheryl Gillett, Yin Wu, Aadil A Khan, Alan A Melcher, Roberto Salgado, Mitchell Dowsett, Andrew N J Tutt, Ioannis Roxanis, Syed Haider, Sheeba Irshad
Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy-Resistant Early Breast Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (20) (2022)
Laura Gómez-Cuadrado, Esme Bullock, Zeanap Mabruk, Hong Zhao, Margarita Souleimanova, Pernille Rimmer Noer, Arran K Turnbull, Claus Oxvig, Nicholas Bertos, Adam Byron, J Michael Dixon, Morag Park, Syed Haider, Rachael Natrajan, Andrew H Sims, Valerie G Brunton
Characterisation of the Stromal Microenvironment in Lobular Breast Cancer. Cancers 14 (4) (2022)
John Alexander, Odette Mariani, Celine Meaudre, Laetitia Fuhrmann, Hui Xiao, Kalnisha Naidoo, Andrea Gillespie, Ioannis Roxanis, Anne-Vincent Salomon, Syed Haider, Rachael Natrajan
Assessment of the Molecular Heterogeneity of E-Cadherin Expression in Invasive Lobular Breast Cancer. Cancers 14 (2) (2022)
Irene Y Chong, Naureen Starling, Alistair Rust, John Alexander, Lauren I Aronson, Marta Llorca-Cardenosa, Ritika Chauhan, Asif Chaudry, Sacheen Kumar, Kerry Fenwick, Ioannis Assiotis, Nik Matthews, Ruwaida Begum, Andrew Wotherspoon, Monica Terlizzo, David Watkins, Ian Chau, Christopher J Lord, Syed Haider, Sheela Rao, David Cunningham
The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing. Journal of clinical medicine 10 (2) (2021)
Diana Zatreanu, Helen M R Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, Diego Grande, Vera Grinkevich, Robert A Heald, Sophie Langdon, Jayesh Majithiya, Claire L McWhirter, Niall M B Martin, Shaun Moore, Joana Neves, Eeson Rajendra, Marco Ranzani, Theresia Schaedler, Martin Stockley, Kimberley Wiggins, Rachel Brough, Sandhya Sridhar, Aditi Gulati, Nan Shao, Luned M Badder, Daniela Novo, Eleanor G Knight, Rebecca Marlow, Syed Haider, Elsa Callen, Graeme Hewitt, Joost Schimmel, Remko Prevo, Christina Alli, Amanda Ferdinand, Cameron Bell, Peter Blencowe, Chris Bot, Mathew Calder, Mark Charles, Jayne Curry, Tennyson Ekwuru, Katherine Ewings, Wojciech Krajewski, Ellen MacDonald, Hollie McCarron, Leon Pang, Chris Pedder, Laurent Rigoreau, Martin E Swarbrick, Ed Wheatley, Simon Willis, Ai Ching Wong, Andre Nussenzweig, Marcel Tijsterman, Andrew Tutt, Simon J Boulton, Geoff S Higgins, Stephen J Pettitt, Graeme C M Smith, Christopher J Lord
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nature communications 12 (1) (2021)
Shirleny Romualdo Cardoso, Andrea Gillespie, Syed Haider, Olivia Fletcher
Functional annotation of breast cancer risk loci: current progress and future directions. British journal of cancer (2021)
Helen Sheldon, John Alexander, Esther Bridges, Lucia M Moreira, Svetlana Reilly, Koon Hwee Ang, Dian Wang, Salwa Lin, Syed Haider, Alison H Banham, Adrian L Harris
ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype. International journal of molecular sciences 22 (20) (2021)
Hans Prakash Sathasivam, Ralf Kist, Philip Sloan, Peter Thomson, Michael Nugent, John Alexander, Syed Haider, Max Robinson
Predicting the clinical outcome of oral potentially malignant disorders using transcriptomic-based molecular pathology. British journal of cancer 125 (3) (2021)
Saira Khalique, Sarah Nash, David Mansfield, Julian Wampfler, Ayoma Attygale, Katherine Vroobel, Harriet Kemp, Richard Buus, Hannah Cottom, Ioannis Roxanis, Thomas Jones, Katharina von Loga, Dipa Begum, Naomi Guppy, Pradeep Ramagiri, Kerry Fenwick, Nik Matthews, Michael J F Hubank, Christopher J Lord, Syed Haider, Alan Melcher, Susana Banerjee, Rachael Natrajan
Quantitative Assessment and Prognostic Associations of the Immune Landscape in Ovarian Clear Cell Carcinoma. Cancers 13 (15) (2021)
Ute Jungwirth, Antoinette van Weverwijk, Rachel J Evans, Liam Jenkins, David Vicente, John Alexander, Qiong Gao, Syed Haider, Marjan Iravani, Clare M Isacke
Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nature communications 12 (1) (2021)
Erle M Holgersen, Andrea Gillespie, Olivia C Leavy, Joseph S Baxter, Alisa Zvereva, Gareth Muirhead, Nichola Johnson, Orsolya Sipos, Nicola H Dryden, Laura R Broome, Yi Chen, Igor Kozin, Frank Dudbridge, Olivia Fletcher, Syed Haider
Identifying high-confidence capture Hi-C interactions using CHiCANE. Nature protocols 16 (4) (2021)
Ilirjana Bajrami, Callum Walker, Dragomir B Krastev, Daniel Weekes, Feifei Song, Andrew J Wicks, John Alexander, Syed Haider, Rachel Brough, Stephen J Pettitt, Andrew N J Tutt, Christopher J Lord
Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency. Communications biology 4 (1) (2021)
Zhong Y Yeow, Bramwell G Lambrus, Rebecca Marlow, Kevin H Zhan, Mary-Anne Durin, Lauren T Evans, Phillip M Scott, Thao Phan, Elizabeth Park, Lorena A Ruiz, Daniella Moralli, Eleanor G Knight, Luned M Badder, Daniela Novo, Syed Haider, Catherine M Green, Andrew N J Tutt, Christopher J Lord, J Ross Chapman, Andrew Jon Holland
Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer. Nature 585 (7825) (2020)
Matteo Morotti, Christos E Zois, Rokaya El-Ansari, Madeleine L Craze, Emad A Rakha, Shih-Jung Fan, Alessandro Valli, Syed Haider, Deborah C I Goberdhan, Andrew R Green, Adrian L Harris
Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer. British journal of cancer 124 (2) (2020)
David M Favara, Christos E Zois, Syed Haider, Elisabete Pires, Helen Sheldon, James McCullagh, Alison H Banham, Adrian L Harris
ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile. Metabolites 9 (12) (2019)
Natalie S Fox, Syed Haider, Adrian L Harris, Paul C Boutros
Landscape of transcriptomic interactions between breast cancer and its microenvironment. Nature communications 10 (1) (2019)
Syed Haider, Cindy Q Yao, Vicky S Sabine, Michal Grzadkowski, Vincent Stimper, Maud H W Starmans, Jianxin Wang, Francis Nguyen, Nathalie C Moon, Xihui Lin, Camilla Drake, Cheryl A Crozier, Cassandra L Brookes, Cornelis J H van de Velde, Annette Hasenburg, Dirk G Kieback, Christos J Markopoulos, Luc Y Dirix, Caroline Seynaeve, Daniel W Rea, Arek Kasprzyk, Philippe Lambin, Pietro Lio', John M S Bartlett, Paul C Boutros
Pathway-based subnetworks enable cross-disease biomarker discovery. Nature communications 9 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Syed Haider