Rationale and design of the Diet Restriction and Exercise-induced Adaptations in Metastatic breast cancer (DREAM) study: a 2-arm, parallel-group, phase II, randomized control trial of a short-term, calorie-restricted, and ketogenic diet plus exercise during intravenous chemotherapy versus usual care.
Amy A KirkhamKaren KingAnil A JoyAndré B PelletierJohn R MackeyKelvin YoungXiaofu ZhuJudith Meza-JuncoSanraj K BasiJulie Price HillerTina BrkinBonnie MichalowskiEdith PituskinD Ian PatersonKerry S CourneyaRichard B ThompsonCarla M PradoPublished in: BMC cancer (2021)
ClinicalTrials.gov, NCT03795493 , registered 7 January, 2019.
Keyphrases
- phase ii
- metastatic breast cancer
- open label
- clinical trial
- weight loss
- physical activity
- double blind
- placebo controlled
- high intensity
- phase iii
- healthcare
- palliative care
- squamous cell carcinoma
- randomized controlled trial
- resistance training
- high dose
- quality improvement
- study protocol
- locally advanced
- radiation therapy
- chronic pain
- pain management